Contributing to the advancement of novel cancer models at the EACR Goodbye Flat Biology meeting

October 12, 2023

3R-US network PhDs and their team members presenting their work and learning about the next generation of cancer models and emerging topics in the areas of cell architecture, mechanobiology, the immune microenvironment, intravital imaging and high-content analysis for cancer therapeutics.

This edition of the conference has seeked to emphasize complex 3D model systems that capture the dialogue between cancer cells, the cellular stroma (e.g. fibroblasts, immune cells), and the extracellular matrix, with a focus on how this dialogue affects cancer progression and treatment response. 

The focus of the meeting is more than fitting to our 3R-US network goals of developing versatile non-animal platforms for the testing of novel biotherapeutics, with the emphasis on colorectal carcinoma. Stella Asmanidou, one of the three doctoral students of our 3R-US network, presented her work on modeling and treating cetuximab resistance using ex vivo colorectal tumor slices. 

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